Dodecyl maltoside

n-Dodecyl β-D-maltoside (DDM) is a non-ionic detergent widely utilized in biochemistry and structural biology. It features a hydrophilic maltose head group and a hydrophobic dodecyl tail, making it exceptionally effective at solubilizing and stabilizing integral membrane proteins while preserving their native structures and functional activities. DDM is an indispensable tool for the crystallization and biochemical characterization of complex membrane-bound macromolecular assemblies.

Suzhou Henra Biotechnology Co., Ltd. manufactures ultra-pure DDM suitable for sensitive protein research, ensuring minimal background interference for downstream biophysical applications.

Function: A mild, non-denaturing surfactant that stabilizes membrane protein complexes during extraction and purification.

Research Significance: Critical for structural biology applications, particularly cryo-electron microscopy (cryo-EM) and X-ray crystallography of challenging membrane proteins.